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Activation of microglia and astrocytes is not just a response to injury, but can also be influenced by chronic stress

The observations from our animal studies prompted us to examine whether dysregulated cellular glutathione homeostasis could render hepatocytes susceptible to TNF-induced cell death

These contrasting effects of LS and OS underscore the context-dependent dual role of AMPK in metabolic regulation and imply a protective function of PRKAA1/AMPK1 against atherosclerosis

The combination is used in in vitro research examining potential additive or synergistic effects at the molecular level

10.1007/978-1-4939-0320-7_33 217 ZhuX.LiB.LouP.DaiT.ChenY.ZhugeA.et al

Unlike single-target supplements, its multimodal mechanism addresses multiple aspects of brain health simultaneously: neuroprotection, neurotrophic support, anti-neuroinflammation, and neuroplasticity